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1. Total population
  • In 2016, 1% (2.4 million) of the US adult population were chronically infected with HCV
2. Current and former PWID
  • 80% of these aquired their infections through IDU
  • 53.1% of current PWID are infected with HCV in 2016
3. Scaling to a population (assuming a steady PWID population)
  • In 2007 there were 2,248,500 PWID (current)
  • In 2016 there were 1,193,954 (0.531*2,248,500) HCV infected PWID (current)
  • In 2016 there were 726,046 (0.8* 2.4million - above) HCV infected former PWID
4. Scaling to a population (assuming a growing PWID population)
  • In 2007 there were 2,248,500 PWID (current)
  • Allow PWID population to grow as a model fitting parameter
5. Incidence trend scaling fitted as a multiplier for probability of infection
6. General population (excluding current and former PWID
  • General population (20% of 2.4 million) of 480,000 chronically infected HCV subjects in 2016
7. Endemic trend for general population
  • Chronic HCV is assumed to be endemic in the general population and in steady state, i.e. constant
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