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- In 2016, 1% (2.4 million) of the US adult population were chronically infected with HCV

- 80% of these aquired their infections through IDU
- 53.1% of current PWID are infected with HCV in 2016

- In 2007 there were 2,248,500 PWID (current)
- In 2016 there were 1,193,954 (0.531*2,248,500) HCV infected PWID (current)
- In 2016 there were 726,046 (0.8* 2.4million - above) HCV infected former PWID

- In 2007 there were 2,248,500 PWID (current)
- Allow PWID population to grow as a model fitting parameter

- General population (20% of 2.4 million) of 480,000 chronically infected HCV subjects in 2016

- Chronic HCV is assumed to be endemic in the general population and in steady state, i.e. constant

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